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Paper ID: 1311

Use of Data Provenance and the Grid in Medical Image Analysis and Drug Discovery - An IXI Exemplar
Keith J,Brooks Jacky B,Buckton Kumar,Changani Joseph V,Hajnal Rolf A,Heckemann Derek L G,Hill Mark,Holden Kelvin K,Leung David G,Reid Daniel,Rueckert Nadeem,Saeed

Appeared in: Proceedings of the UK e-Science All Hands Conference 2004 website: http://www.allhands.org.uk/2004/
Page Numbers:179 - 187
Publisher: Engineering and Physical Sciences Research Council
Year: 2004
ISBN/ISSN: 1-904425-21-6
Contributing Organisation(s):
Field of Science: e-Science

URL: http://www.allhands.org.uk/2004/proceedings/papers/100.pdf

Abstract: Medical research and drug discovery rely increasingly on comparisons between magnetic resonance images from large numbers of subjects, often with multiple time points for each subject. We applied image registration and visualisation techniques for quantitative and qualitative assessment of changes over time in an experimental model of rheumatoid arthritis. We used the Grid to enable remote invocation and parallel execution of the algorithms. Data provenance was stored in a database to provide information about the validity, accuracy and timeliness of the data, which establishes a data integrity framework that is very important in the process of drug discovery and development.

Keywords: e-Science, AHM 2004


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