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Paper ID: 1563

e-Science Tools For The Genomic Scale Characterisation Of Bacterial Secreted Proteins
Tracy,Craddock Phillip,Lord Colin R,Harwood Anil,Wipat

Appeared in: Proceedings of the UK e-Science All Hands Conference 2006 website: http://www.allhands.org.uk/2006/
Page Numbers:788 - 796
Publisher: National e-Science Centre
Year: 2006
ISBN/ISSN: 0-9553988-0-0
Contributing Organisation(s):
Field of Science: e-Science

URL: http://www.allhands.org.uk/2006/proceedings/papers/709.pdf

Abstract: Within bioinformatics, a considerable amount of time is spent dealing with three problems; heterogeneity, distribution and autonomy. In this paper we focus on the strengths and some weaknesses of current eScience technology in addressing these problems by considering the application of e-Science workflows and a service oriented approach to the genomic scale prediction and characterisation of secreted proteins from bacteria. Predictions were automatically integrated into a custom relational database with an associated Web portal to facilitate expert curation, results browsing and querying. We describe the use of workflow technology to arrange secreted proteins into families and study the relationships between these families. The design of the workflows, the architecture and the reasoning behind our approach are discussed.

Keywords: e-Science, AHM 2006


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