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Paper ID: 1720

Lightwieght Solution for Protein Annotation
Shikta,Das A Stephen,McGough Jeremy,Cohen John,Darlington

Appeared in: Proceedings of the UK e-Science All Hands Conference 2005 website: http://www.allhands.org.uk/2005/
Page Numbers:
Publisher: Engineering and Physical Sciences Research Council
Year: 2005
ISBN/ISSN: 1-904425-53-4
Contributing Organisation(s):
Field of Science: e-Science

URL: http://www.allhands.org.uk/2005/proceedings/papers/512.pdf

Abstract: Imperial College e-Science Networked Infrastructure (ICENI) is an end-to-end Grid middleware developed to allow transparent usage of Grid. It consists of both a service-oriented Grid middleware and an application toolkit, using a component-programming model to represent Grid applications. We utilise this infrastructure in the the e-Protein project, a Biotechnology and Biological Sciences Research Council pilot project, which provides structure-based annotation of proteins in the major genomes by linking remote resources at three different sites. The annotation utilises homology and fold recognition methods to assign protein structures to the proteomes. We have taken the approach of modularising applications into inter-connected components and running each application through a workflow manager, which executes the components in the specified manner. A web interface provides a user-friendly front end to the Grid system, where users can request their choice for the annotation and check previous annotations from the database.

Keywords: e-Science, AHM 2005


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