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Paper ID: 2499

Secure, Reliable and Dynamic Access to Distributed Clinical Data
Stell,A.J Sinnott,R.O Ajayi,O

Appeared in: The Third International Life Science Grid Workshop 2006 (LSGrid2006), Riken Institute, Japan (http://www.lsgrid.org/2006/)
Page Numbers:
Publisher: N/A
Year: 2006
ISBN/ISSN:
Contributing Organisation(s):
Field of Science: e-Science

URL: http://www.nesc.ac.uk/papers/staff/LSGrid2006_VOTES-cameraready.pdf

Abstract: An abundance of statistical and scientific data exists in the area of clinical and epidemiological studies. Much of this data is dis- tributed across regional, national and international boundaries with dif- ferent policies on access and usage, and a multitude of different schemata for the data often complicated by the variety of supporting clinical cod- ing schemes. This prevents the wide scale collation and analysis of such data as is often needed to infer clinical outcomes and to determine the often moderate effect of drugs. Through grid technologies it is possi- ble to overcome the barriers introduced by distribution of heterogeneous data and services. However reliability, dynamicity and fine-grained secu- rity are essential in this domain, and are not typically offered by current grids. The MRC funded VOTES project (Virtual Organisations for Trials and Epidemiological Studies) has implemented a prototype infrastruc- ture specifically designed to meet these challenges. This paper describes this on-going implementation effort and the lessons learned in building grid frameworks for and within a clinical environment.

Keywords: Security, Data Federation, Clinical Trials, Grid


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